Evaluation of the Cytotoxic and Genotoxic Potential of Khat (Catha edulis Forsk) Extracts on Human T Lymphoblastoid Cell Line
نویسندگان
چکیده
منابع مشابه
Catha edulis Forsk. (Khat): Evaluation of its Antidepressant-like Activity
BACKGROUND Catha edulis Forsk. (Khat) is traditionally used for treating various disorders. Nevertheless there are no reports of any scientific assessment of its psychopharmacological properties. OBJECTIVE Therefore, the current study was designed to evaluate the antidepressant-like activity of Khat ethanolic extract using established animal models of depression and stress. MATERIALS AND ME...
متن کاملAssessment of khat (Catha edulis Forsk) 1. Substance Identification
F. WHO Review History: The WHO Expert Committee on Drug Dependence (ECDD) and other UN bodies reviewed khat at earlier occasions. The Advisory Committee on the Traffic in Opium and Other Dangerous Drugs of the League of Nations discussed on the subject in 1933, but no action was taken. On request of the Commission on Narcotics Drugs (CND), the Expert Committee on Addiction-Producing Drugs (as t...
متن کاملKhat (Catha edulis Forsk.) Dependence Potential and Pattern of Use in Saudi Arabia
BACKGROUND Catha edulis Forsk. (Khat) is used for its psychoactive effects among people in Africa and the Arabian Peninsula, although its utilization is illegal in some countries such as Saudi Arabia. This study examined the pattern of Khat use and assessed the applicability of the Drug Abuse Screening Test-10 (DAST-10) to measure Khat dependence. METHODS A pretested questionnaire was used to...
متن کاملIn vitro hepatotoxcity of Catha edulis Forsk. (khat) phenolic-rich extract on human hepatocytes
Article history: Received on: 09/12/2013 Revised on: 18/01/2014 Accepted on: 03/03/2014 Available online: 27/11/2014 In our previous research, Khat has been shown to be associated with hepatic hypertrophy and hepatotoxicity in male and female SD-rats. However, no in vitro studies have been previously done to test on hepatotoxicity of khat on human experimental models. In vitro toxicological eva...
متن کاملChemistry, Pharmacology, and Toxicology of Khat (Catha Edulis Forsk): A Review
Catha edulis (khat) is a plant grown commonly in the horn of Africa. The leaves of khat are chewed by the people for its stimulant action. Its young buds and tender leaves are chewed to attain a state of euphoria and stimulation. Khat is an evergreen shrub, which is cultivated as a bush or small tree. The leaves have an aromatic odor. The taste is astringent and slightly sweet. The plant is see...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Medical Sciences
سال: 2004
ISSN: 1682-4474
DOI: 10.3923/jms.2004.110.114